The 29-year-old England captain appeared to be in pain after that Murtaza Bouraliganji I brought it down with a Kamui tackle three minutes into the second half on Monday.
Kane managed to stay on the field until the 75th minute, when he was replaced by his fellow striker Callum Wilson.
After the match, Kane was walking with a slight laceration on his right ankle and a slight limp.
Gareth Southgate has played down his fears that Kane could be out for a short spell but the FA is assessing his injury ahead of England’s second group match on Friday.
Southgate said in the aftermath of England’s 6-2 win Iran: “I think Harry’s fine. It looked like a bad tackle but he continued the game. We sent him off because we felt it was a moment in the game that we can do.”
The saga of Harry Kane’s troublesome ankles, and why Tottenham might be ready to deal with his absence
The current England No. 9 needs three more goals to become England’s all-time top scorer.
He currently has 51 goals in 76 matches for his country.
Analysis of Harry Kane’s quiet efficiency: 19 touches, nine assists and two assists
(Photo: Liu Lu/VCG via Getty Images)
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